tomjakubowski
As mentioned, Wolfram livestreams some of his working sessions on Twitch, he calls it "Live CEOing". I put it on sometimes in the background while remote working; it does a great job emulating the in-office effect of having an interesting conversation nearby to tune out, which I find helps me focus.

https://twitch.tv/videos/2151617315

chipz
fiforpg
One thing I remember liking in this post was his personal homepage (a little further down). There has been a recent HN discussion of Glance, a personal dashboard, but Wolfram's seemed more effective.
ilrwbwrkhv
He has found the ultimate hack in living in a modern capitalistic economy. Have a private company which has a cash cow and allows you to work on whatever projects you want and has less than a thousand employees.

Even valve is somewhat similar and they produce some of the most interesting, unique things without having to bend a knee for shareholders.

dan-g
(2019)—Would be curious to see how his setup has changed post-LLM.